Daniel Barolet, Pascale Duplay, Helene Jacomy, and Mathieu Auclair The influence of emission parameters in low-level-light therapy on cellular responses is not yet fully understood. This study assessed the impact of various light delivery modes on collagen production in human primary fibroblast cultured in monolayers after three treatments with red light-emitting d ... [J. Biomed. Opt. 15, 048005 (2010)] published Tue Aug 10, 2010.
Harsha E. Rajapakse, Nivriti Gahlaut, Shabnam Mohandessi, Dan Yu, Jerrold R. Turner et al. Forster resonance energy transfer (FRET) with fluorescent proteins permits high spatial resolution imaging of proteinprotein interactions in living cells. However, substantial non-FRET fluorescence background can obscure small FRET signals, making many potential interactions unobservable by convent ... [Proc. Natl. Acad. Sci. U.S.A. 107, 13582 (2010)] published Wed Aug 4, 2010.
Rituparna Sinha Roy, Shivani Soni, Rania Harfouche, Pooja R. Vasudevan, Oliver Holmes et al. Therapeutic angiogenesis is an emerging paradigm for the management of ischemic pathologies. Proangiogenic Therapy is limited, however, by the current inability to deliver angiogenic factors in a sustained manner at the site of pathology. In this study, we investigated a unique nonglycosylated acti ... [Proc. Natl. Acad. Sci. U.S.A. 107, 13608 (2010)] published Wed Aug 4, 2010.
Shutao Guo, Yong Qiao, Weiwei Wang, Haiyong He, Liandong Deng et al. pH-dependent temperature- sensitive poly(epsilon-caprolactone)-graft-poly(2-(dimethylamino) ethyl methacrylate) (PCL-g-PDMAEMA), a kind of degradable, amphiphilic, cationic copolymer, was synthesized. PCL-g-PDMAEMA was self-assembled into core-shell nanoparticles with an ultralow critical associatio ... [J. Mater. Chem. 20, 6935 ] published .
Ranran Wang, Jing Sun, Lian Gao, and Jing Zhang Single-walled carbon nanotubes dispersed by pristine DNA and denatured DNA were used to prepare transparent conductive films on PET substrates by a vacuum filtration and spray coating method. Transmission electron microscopy (TEM) was used to characterize the dispersion state of SWCNT solutions. X-r ... [J. Mater. Chem. 20, 6903 ] published .
Jinghua Chen, Jing Zhang, Juan Li, Fengfu Fu, Huang-Hao Yang et al. Based on the nicking endonuclease assisted detection strategy, a novel electrochemical biosensor for the sequence-specific detection of DNA with ultrahigh sensitivity and selectivity is developed. By employing the above strategy, this DNA biosensor can detect as low as 0.068 fM target DNA and exhibi ... [Chem. Commun. 46, 5939 (2010)] published Wed Aug 4, 2010.
Xing Liang, Steven G. Adie, Renu John, and Stephen A. Boppart A dynamic spectral-domain optical coherence elastography (OCE) imaging technique is reported. In this technique, audio-frequency compressive vibrations are generated by a piezoelectric stack as external excitation, and strain rates in the sample are calculated and mapped quantitatively using phase-s ... [Opt. Express 18, 14183 (2010)] published Thu Aug 5, 2010.
Long Zhang, Steven Staelens, Roel Van Holen, Jeroen Verhaeghe, and Stefaan Vandenberghe Purpose: Studies have shown that Monte Carlo-based reconstruction could effectively improve the image quality of positron emission tomography. The authors have previously used a Gaussian rotator-based algorithm to efficiently reduce the computational cost for system matrix (SM) calculation and to me ... [Med. Phys. 37, 4648 (2010)] published Wed Aug 11, 2010.
Claudia Schmidt and Viola Vogel A central challenge on the way to engineer novel materials and nanodevices comprising active transport by nanomotors is the integration of cargo loading and unloading stations on one chip. Exploiting DNA hybridization in zipping and shearing geometries, we demonstrate spatially distinct cargo pick-u ... [Lab Chip 10, 2195 (2010)] published Wed Aug 11, 2010.
Jana M. Kainerstorfer, Martin Ehler, Franck Amyot, Moinuddin Hassan, Stavros G. Demos et al. Multispectral images of skin contain information on the spatial distribution of biological chromophores, such as blood and melanin. From this, parameters such as blood volume and blood oxygenation can be retrieved using reconstruction algorithms. Most such approaches use some form of pixelwise or vo ... [J. Biomed. Opt. 15, 046007 (2010)] published Mon Aug 2, 2010.
Vedran Kajic, Boris Povazay, Boris Hermann, Bernd Hofer, David Marshall et al. A novel statistical model based on texture and shape for fully automatic intraretinal layer segmentation of normal retinal tomograms obtained by a commercial 800nm optical coherence tomography (OCT) system is developed. While existing algorithms often fail dramatically due to strong speckle noise, n ... [Opt. Express 18, 14730 (2010)] published Thu Aug 5, 2010.
K. S. Morgan, K. K. W. Siu, and D. M. Paganin We examine the projection approximation in the context of propagation-based phase contrast imaging using hard x-rays. Specifically, we consider the case of a cylinder or a rounded edge, as a simple model for the edges of many biological samples. The Argand-plane signature of a propagation-based phas ... [Opt. Express 18, 9865 (2010)] published Thu Aug 5, 2010.
Xiaoxing Han and Edward Brown In this paper, we present a method to determine, for the first time, the ratio of forward-propagating second harmonic (SHG) signal to back-propagating SHG signal (F/B) in vivo on the surface of intact tissue samples without any biopsy or tissue sectioning, using only epidetection (i.e., via a single ... [Opt. Express 18, 10538 (2010)] published Thu Aug 5, 2010.
Ahmet F. Coskun, Ikbal Sencan, Ting-Wei Su, and Aydogan Ozcan We demonstrate the use of a compressive sampling algorithm for on-chip fluorescent imaging of sparse objects over an ultra-large field-of-view (>8 cm) without the need for any lenses or mechanical scanning. In this lensfree imaging technique, fluorescent samples placed on a chip are excited through ... [Opt. Express 18, 10510 (2010)] published Thu Aug 5, 2010.
Arnau Farre, Carol Lopez-Quesada, Jordi Andilla, Estela Martin-Badosa, and Mario Montes-Usategui Optical tweezer experiments have partially unveiled the mechanical properties of processive motor proteins while driving polystyrene or silica microbeads in vitro. However, the set of forces underlying the more complex transport mechanisms in living samples remains poorly understood. Several studies ... [Opt. Eng. 49, 085801 (2010)] published Fri Aug 13, 2010.
Tao Lu, Qing Xiao, Danqing Xia, Kai Ruan, and Zhengjia Li To overcome the inconsecutive drawback of shadow and schlieren photography, the complete dynamics of cavitation bubble oscillation or ablation products induced by a single holmium laser pulse [2.12 [mu]m, 300 [mu]s (FWHM)] transmitted in different core diameter (200, 400, and 600 [mu]m) fibers is ... [J. Biomed. Opt. 15, 048002 (2010)] published Thu Aug 5, 2010.
Heidy Sierra, Dana Brooks, and Charles DiMarzio The extraction of 3-D morphological information about thick objects is explored in this work. We extract this information from 3-D differential interference contrast (DIC) images by applying a texture detection method. Texture extraction methods have been successfully used in different applications ... [J. Biomed. Opt. 15, 046021 (2010)] published Tue Aug 10, 2010.
Ya-Yuan Fu, Chih-Hsuan Lu, Chi-Wen Lin, Jyuhn-Huarng Juang, Grigori Enikolopov et al. Microscopic visualization of islets of Langerhans under normal and diabetic conditions is essential for understanding the pathophysiology of the disease. The intrinsic opacity of pancreata, however, limits optical accessibility for high-resolution light microscopy of islets in situ. Because the stan ... [J. Biomed. Opt. 15, 046018 (2010)] published Wed Aug 4, 2010.
Cheng Wang, Xudong Guo, Baoying Fang, and Chengli Song A fiber confocal backscattering (FCBS) spectrometer is developed based on fiber confocal microscopy and light scattering theory. The FCBS spectrometer can provide imaging and spectral information simultaneously at the cellular scale. Normal stomach epithelial cell line GES-1 and cancerous cell line ... [J. Biomed. Opt. 15, 040505 (2010)] published Wed Aug 11, 2010.
Kai Yang and Jie Wu This paper presents a numerical study of a preconcentrator design that can effectively increase the binding rate at the sensor in a real time manner. The particle enrichment is realized by the ac electrothermal (ACET) effect, which induces fluid movement to carry nanoparticles toward the sensor. The ... [Biomicrofluidics 4, 034106 (2010)] published Thu Aug 12, 2010.
